Biodegradable microcapsules designed via 'click' chemistry.
نویسندگان
چکیده
Dextrans modified with alkyne and azide groups through hydrolysable carbonate esters form degradable microcapsules after Cu(I) catalysed 'click' reaction between azides and alkynes yielding triazole cross-links.
منابع مشابه
Synthesis and click chemistry of a new class of biodegradable polylactide towards tunable thermo-responsive biomaterials.
A new class of clickable and biodegradable polylactide was designed and prepared via bulk polymerization of 3,6-dipropargyloxymethyl-1,4-dioxane-2,5-dione (1) which was synthesized from easily accessible propargyloxylactic acid (5). A homopolymer of 1 and random copolymer of 1 with l-lactide were obtained as amorphous materials and exhibit low Tg of 8.5 and 34 °C, respectively, indicating their...
متن کاملClick chemistry plays a dual role in biodegradable polymer design.
Click chemistry plays a dual role in the design of new citrate-based biodegradable elastomers (CABEs) with greatly improved mechanical strength and easily clickable surfaces for biofunctionalization. This novel chemistry modification strategy is applicable to a number of different types of polymers for improved mechanical properties and biofunctionality.
متن کاملEncapsulation of grape seed extract in polylactide microcapsules for sustained bioactivity and time-dependent release in dental material applications.
OBJECTIVE To sustain the bioactivity of proanthocyanidins-rich plant-derived extracts via encapsulation within biodegradable polymer microcapsules. METHODS Polylactide microcapsules containing grape seed extract (GSE) were manufactured using a combination of double emulsion and solvent evaporation techniques. Microcapsule morphology, size distribution, and cross-section were examined via scan...
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ورودعنوان ژورنال:
- Chemical communications
دوره 2 شماره
صفحات -
تاریخ انتشار 2008